| Product Name | Isochlorogenic acid A |
|---|---|
| CAS | 2450-53-5 |
| Formula | C25H24O12 |
| MW | 516.45 |
| Boiling point | 826.2±65.0 °C | Condition: Press: 760 Torr |
| PKa | 3.54±0.50 | Condition: Most Acidic Temp: 25 °C |
| Product Name | Isochlorogenic acid A |
|---|---|
| CAS | 2450-53-5 |
| Formula | C25H24O12 |
| MW | 516.45 |
| Boiling point | 826.2±65.0 °C | Condition: Press: 760 Torr |
| PKa | 3.54±0.50 | Condition: Most Acidic Temp: 25 °C |
WKQ-0030236
中文名稱：異綠原酸A
中文別名：3,5-O-二咖啡酰奎寧酸；(-)-3,5-二咖啡酰奎寧酸
英文名稱：Isochlorogenic acid A
英文別名：Cinnamic acid, 3,4-dihydroxy-, 5-carboxy-2,5-dihydroxy-1,3-cyclohexylene ester (8CI);Cyclohexanecarboxylic acid, 3,5-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4-dihydroxy-, (1α,3R,4α,5R)- (9CI);Cyclohexanecarboxylic acid, 3,5-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4-dihydroxy-, [1R-(1α,3α,4α,5β)]-;(1α,3R,4α,5R)-3,5-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4-dihydroxycyclohexanecarboxylic acid;Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, 3,5-bis(3,4-dihydroxycinnamate) (8CI);3,5-Dicaffeoylquinic acid;3,5-Dicaffeylquinic acid;CJ 4-16-4;Isochlorogenic acid a;Quinic acid 3,5-di-O-caffeate;
分子式：C25H24O12
分子量：516.45
CAS號：2450-53-5
純度：HPLC≥98%
沸點：826.2±65.0 °C | Condition: Press: 760 Torr
密度：1+-.0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
酸系度數(shù)：3.54±0.50 | Condition: Most Acidic Temp: 25 °C
儲存條件：-20℃，干燥、避光、密封
規(guī)格：5mg10mg20mg50mg100mg500mg1g2g等應客戶需求包裝
供應單位：四川省維克奇生物科技有限公司
供應電話：028-81700200/4008005713
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| Anti-inflammatory/anti-oxidant properties and the UPLC-QTOF/MS-based metabolomics discrimination of three yellow camellia species | ||
| Source:SCI：FOOD RESEARCH INTERNATIONAL | Author:Mingming Zhao | Notes：影響因子：7.425 |
| Reference description | ||
Procyanidin B3, vicenin2, astilbin, kaempferol-3-sophoroside-7-rhamnoside, isoquercitrin, isochlorogenic acid A, rutin, cynaroside, hyperoside, genistein, kaempfeol-3-O-rutinoside, quercetin, kaempferol, catechin, (-)-epicatechin, luteolin, vitexin, oleanolic acid, and isookanin-7-O-glucoside (the purities of all standards were higher than 99 % by HPLC analysis) were purchased from Weikeqi-biotech Co., ltd. (Chengdu, Sichuan, China). Dimethyl sulfoxide (DMSO), lipopolysaccharides (LPS) from Escherichia coli O111:B4 and 3-[4,5-Dimethyl-2-thiazolyl]-2,5-diphenyltetrazolium bromide (MTT) were purchased from Sigma-Aldrich (St. Louis, MO, USA). | ||
| Chemical fingerprint analysis and identification of Dendranthema lavandulifolium buds | ||
| Source:SCI：INDUSTRIAL CROPS AND PRODUCTS | Author:Xinfeng Zhang | Notes：影響因子：3.849 |
| Reference description | ||
All other chemicals and extraction solvents used were of analytical grade and purchased from Sinopharm Chemical Reagent Co., Ltd. (Beijing, China). Ten chemical standards were purchased from Weikeqi Biological Technology Co, Ltd. (Sichuan, China), including chlorogenic acid (3-CQA), cryptochlorogenic acid (4-CQA), neochlorogenic acid (5-CQA), isochlorogenic acid A (3,5-diCQA), isochlorogenic acid B (3,4-diCQA), isochlorogenic acid C (4, 5-diCQA), eriodictyol-7-O-β-d-glucoside, luteolin-7-O-β-d-glucoside, 5, 7, 4′-trihydroxy-6, 3′, 5′-trimethoxyflavone, eupatilin (purity ≥ 99%). In addition, eriodictyol-7-O-β-d-glucuronide was isolated and purified from Jumi in the laboratory (>98%). All of the stock and working standard solutions were stored at 4?°C until used for the experiments. | ||
| Chemical Profiling and Comparison of Sangju Ganmao Tablet and Its Component Herbs Using Two-Dimensional Liquid Chromatography to Explore Compatibility Mechanism of Herbs | ||
| Source:SCI：Frontiers in Pharmacology | Author:Ji Shuai | Notes：影響因子：3.831 |
| Reference description | ||
The reference standards of isorhmnetin (3), diosmetin (6), isochlorogenic acid A (7), kaempferol (10), quercetin (14), isochlorogenic acid C (15), apigenin (19), forsythin (20), chlorogenic acid (23), liquiritin (25), luteolin-7-O-glucoside (26), astragalin (28), luteolin (29), buddleoside (31), quercetin-3-O-glucoside (33), amygdalin (37), caffeic acid (38), forsythoside A (39), glycyrrhizic acid (40), ferulic acid (42), rutin (44), hyperoside (50), and platycodin D (51) were purchased from Sichuan Weikeqi Biological Technology, Co., Ltd. (Chengdu, China). Mulberry leaf, chrysanthemum, Fructus Forsythiae, licorice, Semen Armeniacae Amarum, Platycodi Radix and Phragmitis Rhizoma | ||
| Multi-Component Analysis of Ilex Kudingcha C. J. Tseng by a Single Marker Quantification Method and Chemometric Discrimination of HPLC Fingerprints | ||
| Source:SCI：MOLECULES | Author:Huan Yi | Notes：影響因子：3.098 |
| Reference description | ||
Tseng and their structures were fully characterized by chemical and spectroscopic methods. The other standards, namely protocatechuic acid (3,4-DA, R3), rutin (R4), neochlorogenic acid (5-CQA, C1), chlorogenic acid (3-CQA, C2), cryptochlorogenic acid (4-CQA, C3), caffeic acid (CA, C4), isochlorogenic acid B (3,4-CQA, C5), isochlorogenic acid A (3,5-CQA, C6) and isochlorogenic acid C (4,5-CQA, C7) were purchased from the National Institute for Food and Drug Control (Beijing, China) or Sichuan Weikeqi Biological Technology Co., Ltd. (Qingjiang, Zhonglu, China) Purity analysis proved to be above 98% by HPLC, and their chemical structures are listed in Figure 7. | ||
| Simultaneous qualitative and quantitative evaluation of Ilex kudingcha C. J. tseng by using UPLC and UHPLC-qTOF-MS/MS | ||
| Source:SCI：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | Author:Jie Zhou | Notes：影響因子：2.831 |
| Reference description | ||
purchased from National Institute for Food and Drug Control (Beijing, China). Neochlorogenic acid (5-CQA, C1), cryptochlorogenic acid (4-CQA, C3), isochlorogenic acid B (3,4-diCQA, C5), isochlorogenic acid A (3,5-diCQA, C6) and isochlorogenic acid C (4,5-diCQA, C7) were bought from Weikeqi Biological Technology Co., Ltd (Sichuan, China). The reference substances of 6-hydroxy-7.7α-dihydrobenzofuran-2(6H)-one (R1), hydroxyl-casein (R2), latifoloside G (K1), kudinoside G (K2), kudinoside A (K3), kudinoside E (R5) | ||
| A UHPLC–MS/MS method for simultaneous determination of twelve constituents from Erigeron breviscapus extract in rat plasma: Application to a pharmacokinetic study | ||
| Source:SCI：JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | Author:Yuanyuan Tian | Notes：影響因子：2.603 |
| Reference description | ||
were supplied from Chengdu Pufeide Biological Technology Co., Ltd. (Sichuan, China). The standards of scutellarin, isochlorogenic acid A, isochlorogenic acid C, and apigenin were purchased from Sichuan Weikeqi Biological Technology Co., Ltd. (Sichuan, China). The internal standard gallic acid (IS1) was purchased from the National Institute for Control of Pharmaceutical | ||
| Pharmacokinetics screening for multi-components absorbed in the rat plasma after oral administration of traditional Chinese medicine Flos Lonicerae Japonicae–Fructus Forsythiae herb couple by sequential negative and positive ionization ultra-high-performance liquid chromatography/tandem triple quadrupole mass spectrometric detection | ||
| Source:SCI：JOURNAL OF CHROMATOGRAPHY A | Author:Wei Zhou | Notes：影響因子：4.258 |
| Reference description | ||
Neochlorogenic acid, cryptochlorogenic acid, 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid and forsythoside B (98% pure) were purchased from Sichuan Weikeqi Bio-tech Co., Ltd. (Sichuan, China). Isoforsythoside, caffeic acid, quinic acid, genistein, luteolin, quercetin, arctigenin, genistin, astragalin, hyperoside, pinoresinol-β-d-glucoside, rutin, isoquercitrin and loganin (98% pure) were | ||
| Effect of chito-oligosaccharide on the oral absorptions of phenolic acids of Flos Lonicerae extract | ||
| Source:SCI：PHYTOMEDICINE | Author:Liuqing Di | Notes：影響因子：2.972 |
| Reference description | ||
purchased from National Institute for the Control of Pharmaceutical and Biological Products. Neochlorogenic acid, cryptochlorogenic acid, 3,4-dicaffeoylquinic acid and 3,5-dicaffeoylquinic acid (98% pure) was purchased from Sichuan Weikeqi Bio-tech Co., Ltd. COS (Fig. 3) was all purchased from Qingdao Honghai Bio-tech Co., Ltd. | ||
| Simultaneous determination of phenolic acids by UPLC–MS/MS in rat plasma and its application in pharmacokinetic study after oral administration of Flos Lonicerae preparations | ||
| Source:SCI：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | Author:Wei Zhou | Notes：影響因子：2.947 |
| Reference description | ||
Chlorogenic acid and tinidazole (using as internal standard, IS) were purchased from National Institute for the Control of Pharmaceutical and Biological Products (Beijing, China). Neochlorogenic acid, cryptochlorogenic acid, 3,4-dicaffeoylquinic acid and 3,5-dicaffeoylquinic acid (98% pure) were purchased from Sichuan Weikeqi Bio-tech Co., Ltd. (Sichuan, China). Six Flos Lonicerae extracts (product A-Jin-Yin-Huang extract, product B-Qing-Re-Jie-Du extract, product C-Fufang Qin-lan extract | ||
| Study on the Rationality for Antiviral Activity of Flos Lonicerae Japonicae-Fructus Forsythiae Herb Couple Preparations Improved by Chito-Oligosaccharide via Integral Pharmacokinetics | ||
| Source:SCI：MOLECULES | Author:Zhou, Wei | Notes：影響因子：2.861 |
| Reference description | ||
Neochlorogenic acid, cryptochlorogenic acid, 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid, and forsythoside B (98% pure) were purchased from Sichuan Weikeqi Bio-tech Co., Ltd. (Sichuan, China). Isoforsythoside (98% pure) was purchased from Chengdu Herbpurify Co., Ltd. (Sichuan, China). Chlorogenic acid and forsythoside A were purchased from the National Institute for the Control of Pharmaceutical and Biological Products (Beijing, China). | ||
| Transepithelial transport of phenolic acids in Flos Lonicerae Japonicae in intestinal Caco-2 cell monolayers | ||
| Source:SCI：Food & Function | Author:Wei Zhou | Notes：影響因子：2.791 |
| Reference description | ||
All voucher specimens were deposited in our laboratory for future reference. Chlorogenic acid, luteoloside and tinidazole (used as an internal standard, IS) were purchased from the National Institute for the Control of Pharmaceutical and Biological Products (Beijing, China). Neochlorogenic acid, cryptochlorogenic acid, 3,4-dicaffeoylquinic acid and 3,5-dicaffeoylquinic acid (98% pure) were purchased from Sichuan Weikeqi Bio-tech Co., Ltd (Sichuan, China). Caffeic acid, quinic acid, genistein, luteolin, quercetin, genistin, hyperoside, isoquercitrin, rutin, dipsacoside B, macranthoidin B and loganin (98% pure) were purchased from Chengdu Herbpurify Co., Ltd (Sichuan, China). | ||
| Comparative pharmacokinetic analysis of extracts of crude and wine-processed Dipsacus asper in rats by a sensitive ultra performance liquid chromatography–tandem mass spectrometry approach | ||
| Source:SCI：JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | Author:Yi Tao | Notes：影響因子：2.687 |
| Reference description | ||
4-Caffeoylquinic acid(4-CQA), chlorogenic acid(3-CQA), 3,5-dicaffeoylquinic acid(3,5-diCQA), loganic acid, loganin, sweroside, dipsacoside B and asperosaponin VI were purchased from Sichuan Weikeqi Biotechnology Co. Chloramphenicol and glycyrrhetinic acid were purchased from Shanghai Yuanye Biological Technology Co. | ||
| Integrating UHPLC–MS/MS quantification and DAS analysis to investigate the effects of wine-processing on the tissue distributions of bioactive constituents of herbs in rats: Exemplarily shown for Dipsacus asper | ||
| Source:SCI：JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | Author:Yi Tao | Notes：影響因子：2.603 |
| Reference description | ||
authenticated by Prof.Cai Baochang, Director of Jiangsu Key Laboratory of Chinese Medicine Processing, Nanjing University of Chinese Medicine. Standard substances were purchased from Sichuan Weikeqi Biotechnology Co located in Chengdu City, Sichuan Province, including 4-caffeoylquinic acid (4-CQA), chlorogenic acid (3-CQA), 3,5-dicaffeoylquinic acid (3,5-diCQA), loganic acid, loganin, and asperosaponin VI. | ||
| UHPLC–MS/MS quantification combined with chemometrics for the comparative analysis of different batches of raw and wine-processed Dipsacus asper | ||
| Source:SCI：JOURNAL OF SEPARATION SCIENCE | Author:Yi Tao | Notes：影響因子：2.557 |
| Reference description | ||
Standard compounds, including 4-caffeoylquinic acid (4-CQA), chlorogenic acid (3-CQA), 3,5-dicaffeoylquinic acid (3,5-diCQA), loganic acid, loganin, sweroside, dipsacoside B, and asperosaponin VI were purchased from Sichuan Weikeqi Biotechnology. Chloramphenicol and glycyrrhetinic acid were obtained from Shanghai Yuanye Biological Technology. The purity of each standard substance was more than 98%. HPLC-grade acetonitrile was obtained from Merck. | ||
| Simultaneous determination of twenty-six components of Flos Lonicerae japonicae–Fructus Forsythiae herb couple using UPLC-ESI-MS/MS: application to its preparations | ||
| Source:SCI：Analytical Methods | Author:Wei Zhou | Notes：影響因子：1.938 |
| Reference description | ||
Chlorogenic acid, luteoloside, pillyrin and forsythoside A were purchased from the National Institute for the Control of Pharmaceutical and Biological Products (Beijing, China). Neochlorogenic acid, cryptochlorogenic acid, 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid and forsythoside B (98% pure) were purchased from Sichuan Weikeqi Bio-tech Co., Ltd. (Sichuan, China). Isoforsythoside, caffeic acid, quinic acid, genistein, luteolin, quercetin, arctigenin, genistin, astragalin, hyperoside, pinoresinol-β-d-glucoside, arctiin, rutin, isoquercitrin, dipsacoside B, macranthoidin B and loganin (98% pure) were purchased from Chengdu Herbpurify Co., Ltd. (Sichuan, China). | ||
| Simultaneous Determination of Ten Bioactive Components in Raw and Processed Radix Dipsaci by UPLC-Q-TOF-MS | ||
| Source:SCI：JOURNAL OF CHROMATOGRAPHIC SCIENCE | Author:Tao Yi | Notes：影響因子：1.216 |
| Reference description | ||
Standard substances, including 4-caffeoylquinic acid (4-CQA), loganic acid, 3,4-dicaffeoylquinic acid (3,4-diCQA), 3,5-dicaffeoylquinic acid (3,5-diCQA), loganin, sweroside and asperosaponin VI were purchased from Sichuan Weikeqi Biotechnology Co. Dipsacussaponin B, asperosaponin V and dipsacoside A were obtained from Nanjing Shizhou Biological Technology Co. The purity of each standard substance was >98%. Their chemical structures are shown in Supplementary Figure S1. | ||
| Study on the Main Components Interaction from Flos Lonicerae and Fructus Forsythiae and Their Dissolution In Vitro and Intestinal Absorption in Rats | ||
| Source:SCI：PLoS One | Author:Wei Zhou | Notes：影響因子：3.534 |
| Reference description | ||
purchased from National Institute for the Control of Pharmaceutical and Biological Products (Beijing, China). Neochlorogenic acid, cryptochlorogenic acid, 3, 4-dicaffeoylquinic acid, 3, 5-dicaffeoylquinic acid and forsythoside B (98% pure) were purchased from Sichuan Weikeqi Bio-tech Co., Ltd. (Sichuan, China). Isoforsythoside, caffeic acid, quinic acid, genistein, luteolin, quercetin, arctigenin, genistin, astragalin, hyperoside, isoquercitrin, pinoresinol-β-D-glucoside, arctiin, rutin, dipsacoside B and loganin | ||
| Simultaneous determination of caffeic acid derivatives by UPLC–MS/MS in rat plasma and its application in pharmacokinetic study after oral administration of Flos Lonicerae–Fructus Forsythiae herb combination | ||
| Source:SCI：JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | Author:Wei Zhou | Notes：影響因子：2.694 |
| Reference description | ||
purchased from National Institute for the Control of Pharmaceutical and Biological Products (Beijing, China). Neochlorogenic acid, cryptochlorogenic acid, 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid and forsythoside B (98% pure) were purchased from Sichuan Weikeqi Bio-tech Co., Ltd. (Sichuan, China). Forsythoside A (98% pure) was purchased from Shanghai Nature Standard Co., Ltd. | ||
